Agadatantra (Toxicology)

1. Derivation, definition of Visha and Agadatantra. Scope of Agadatantra.

Visha Utpatti, Visha Prabhava, Visha Pranaharana Kriya, Visha Guna, Visha Gati, Visha Vega Visha Sankata, Shanka Visha.

2. Definition of toxicology, Definition of poison, suicidal and homicidal poisons, classification of poisons, their action and route of administration, absorption, excretion, metabolism, diagnosis and general principles of treatment, duties of a medical practitioner in case of suspected poisoning.

3. Origin and Classification of Visha:-Its sources, Difference between Visha, Madya and Oja guna, Visha Upadrava and Visha Mukta Lakshana.

Tests for detection of Visha, and Modern Toxicological Techniques of detection of poisons Visha Data Lakshana, Visha Peeta Lakshana, Signs and symptoms of Visha afflicted organs and personal effects. (Poisoning with Anjana, Lepa paduka, Abharana etc.

5. Introduction to Environmental Toxicology- Samuhika Vishaprayoga- effect of chemical and nuclear warfare.

Vishopakrama described by Charak, General principles of Management of poisoning.

7. Manifestation of poisoning due to poisons of plant origin their fatal Dose, fatal period, management of poisoning, post mortem appearance and its medico legal importance.

Visha and Upavisha- Arka, Snuhi, Langali, Karaveera, Gunja, Ahiphena, Dhattura, Bhallataka, Vatsanabha, Kupeelu, Jayapala, Bhanga & Tobacco, Parthenium hysteriphorus, Chitraka, Eranda, Digitalis and Cerebra Odallam.

8. Garavisha, Dooshivisha, Viruddhahara. Food adulteration and poisoning-classification, diagnosis, management and contemporary significance.

9. Jangama Visha – Detailed study of Sarpa, keeta, Loota, Vrischika, Mooshika, Alarka – Visha; Lakshana, Bheda, Chikitsa and their Sadhyasadhyata (contemporary and classical views).

10. Introduction to poisoning due to Acids, Alkalis, metals, Non-metals, Asphyxiants and others, their Fatal Dose, Fatal period, Manifestation, management, medico legal importance and postmortem appearance of poisoning due to:

a) Acid and Alkalis- Sulphuric acid, Hydrochloric acid, Nitric acid, Hydrocyanic acid, Oxalic acid, Carbolic acid, Formic acid, alkalis in general.

b) Asphyxiants – Carbon monoxide, Carbon dioxide, Hydrogen sulphide

c) Nonmetallic poisons – Phosphorous, Iodine

Metallic poisoning – Arsenic, Mercury, Lead, Copper, Zinc, Tin.

d) Others Petroleum Kerosene Organo phosphorus compounds -Aluminum phosphate, Organo Chlorinated Compounds, Household poisons.

11. Madya and Madatyaya. Alcohol poisoning (Ethanol and Methanol).

12. Introduction to Narcotic drugs and Psychotropic substances Act 1985.

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